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Although Cubicus Boxfish are not considered to be very easy to keep in an aquarium some people have had success. The following water conditions in an aquarium of 125 gallons or more are acceptable, 72-78° F, dKH 8-12, pH 8.1-8.4 and sg 1.020-1.025. Most of the reason that people don't like to house these fish in an aquarium is that if they die or become stressed they release a poison called ostracitoxin out of its glands. This substance will sometimes kill the other fish in the tank! As you can imagine in the wild this makes for a serious deterrent. A potential predators will take a taste and then immediately spit out this poisonous fish. In the aquarium though, be sure to take out the dead Cubicus Boxfish as soon as possible and do a water change of at least 50%.
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